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Figure 2 | Genome Integrity

Figure 2

From: Image-based quantitative determination of DNA damage signal reveals a threshold for G2 checkpoint activation in response to ionizing radiation

Figure 2

Phosphorylated histone H2AX foci formed in G2 and mitotic cells. Formation of phosphorylated H2AX foci and phosphorylation of histone H3 were examined in G2 cells and mitotic cells 2 hr after 0.4 Gy of X-rays. Note that G2 cells have weaker intensity and more rugged and discontinuous pattern of phosphorylated histone H3 staining compared to mitotic cells. In contrast, mitotic cells have foci with smaller size and weaker fluorescence intensity than G2 cells.

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Genome Integrity

ISSN: 2041-9414